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“Venter instills awe for biology as it is, and as it might become in our hands.” —Publishers Weekly
On May 20, 2010, headlines around the world announced one of the most extraordinary accomplishments in modern science: the creation of the world’s first synthetic lifeform. In Life at the Speed of Light, scientist J. Craig Venter, best known for sequencing the human genome, shares the dramatic account of how he led a team of researchers in this pioneering effort in synthetic genomics—and how that work will have a profound impact on our existence in the years to come. This is a fascinating and authoritative study that provides readers an opportunity to ponder afresh the age-old question “What is life?” at the dawn of a new era of biological engineering.
- Sales Rank: #265831 in eBooks
- Published on: 2013-10-17
- Released on: 2013-10-17
- Format: Kindle eBook
From Publishers Weekly
Venter (A Life Decoded), a field giant of genetics, makes a persuasive case that synthetic biology will help us understand, appreciate, and improve our own biology. The impatient genius who arrogantly raced the U.S. government to sequence the human genome, Venter scores many firsts in this emerging field, including the creation—nearly from scratch—of the first synthetic bacterium. It was not a pure first, as he used cytoplasm from an existing cell to boot up his synthetic genome—which only deviated slightly from the genome of an existing bacterium. But it&'s a major coup; Venter&'s synthetic genome successfully instructed the cell to create living proteins. We can now change the software of life, which then changes its own hardware, as it were. Venter shares spellbinding stories from the frontiers of genomics—researchers creating living toolboxes out of mechanisms co-opted from varied life forms. For the wary, he notes nature itself mixes and matches species-specific mechanisms: our own mitochondria were once bacteria engulfed by, and incorporated into, our cells. Gene engineering opens new portals of life-designing potential, he argues, and he champions ethics reviews of such work. Venter instills awe for biology as it is, and as it might become in our hands. Agent: John Brockman, Brockman Inc. (Nov.)
From Booklist
When scientists finally succeed in transmitting to another galaxy the digital instructions for building a living organism, they will rely on science that Venter has pioneered. To understand the groundbreaking work Venter has done, however, readers must revisit Hooke’s seventeenth-century discovery of the cell as the primary structure of life and must peer into an anticipated future of teleportation via quantum entanglement. But the narrative largely focuses on the twentieth-century research fulfilling physicist Schrödinger’s hopes of finding the key of life in a biochemical aperiodic crystal. In particular, readers see how the double helix that Watson and Crick first recognized in DNA 60 years ago has become an adaptable scaffold for genetic engineers wielding potent pools for creating new life-forms. Readers will marvel at the potential that genetic engineering holds for making food, purifying water, generating energy, and curing diseases. Though they may wish to consult other sources to explore the philosophical and ethical issues he raises, readers will thank Venter for an insider’s perspective on epoch-making science. --Bryce Christensen
Review
“Life at the Speed of Light provides an important look behind the hyperbolic headlines that often accompany synthetic biology, a guide to the future of life from one of the scientists helping to create it."
~Emily Anthes, The Washington Post
"When scientists finally succeed in transmitting to another galaxy the digital instructions for building a living organism, they will rely on science that Venter has pioneered.... Readers will thank Venter for an insider’s perspective on epoch-making science."
~Booklist
"A fascinating glimpse at a scientific frontier."
~Kirkus Reviews
“Craig Venter is a singular individual... at once inheritor of molecular biology’s prior triumphs and the wellspring of its future…He compellingly depicts his diverse research as a concerted effort to shuttle biology between the material and the digital worlds…a gripping tale and welcome antidote to dry materials and methods sections that make such sagas feel disembodied and inevitable.”
~Science
"Spellbinding stories from the frontiers of genomics.... Venter instills awe for biology as it is, and as it might become in our hands."
~Publishers Weekly
"[A] remarkable book."
~Scientific American
"A great read."
~Ricki Lewis, PhD, PLOS.org
“One of the world's leading scientists delivers a history of molecular biology and its many ramifications depicted as it has been and will continue to be, a creator of the golden age of modern biology. His style is that of a dispatch from the front, urgent and engaged, as only a participant could write it, and the best of its genre since James D. Watson's The Double Helix.”
~Edward O. Wilson, University Research Professor Emeritus, Harvard University
“In 1943 Erwin Schrödinger asked the question “What is life?” Craig Venter decided to find out. The first step in understanding something is to take it apart. The next step is to put it back together. Finally, prove that you haven’t neglected anything by building it yourself from scratch. In this articulate, precise, and uniquely first-person report from the front lines between biology and technology--commendably addressing the role of proteins as well as the nucleotides that code for them--Craig Venter sheds new light on Schrödinger’s question, while explaining how his own pioneering work reading and writing genetic sequences between living cells and computers is enabling life as we know it to take the first steps toward becoming something else. A landmark account.”
~George Dyson, author of Turing's Cathedral and Darwin Among the Machines
“Life at the Speed of Light takes you to the frontier of science to explain the exciting potential of synthetic biology. Craig Venter, one of our most vivid and iconoclastic scientists, weaves the history of our understanding of life with his personal journey as one of the key scientists in decoding the human genome, and now one of the leaders of research into programming DNA and even making synthetic living organisms. It could prove to be one of the most important technologies of this century.”
~Nathan Myhrvold, co-founder of Intellectual Ventures and former Chief Technology Officer of Microsoft
“Humanity is entering a period of radical transformation and one reason is due to Craig Venter's research in creating new life forms based on computer designed synthetic DNA. Life at the Speed of Light is his beautifully written, powerful and persuasive story on how DNA information and computers will blend in the coming singularity, that watershed in the evolution of humanity beyond which amazing new possibilities for life, society and everything we care about will emerge.”
~Ray Kurzweil, author of How to Create a Mind and The Singularity Is Near
Most helpful customer reviews
26 of 29 people found the following review helpful.
A Must Read for those interested in computers and biology
By Josef
The positive:
Lots of up-to-date information on our current understanding of how the code of life, DNA, shapes our destiny. Venter describes is great detail the creation of man-made life in the form of Mycoplasma, "the first living self-replicating species to have a computer as a parent". This was pure science fiction only 20 years ago.
Lots of very-readable historical background information, from Erwin Schroedinger's "What is Life" through many of the key scientific experiments that got us to where we are today.
The (slightly) negative:
Venter's ego sometimes makes him seem somewhat immodest, in my humble opinion.
My recommendation is to read this book in combination with Venter's biography, "A Life Decoded", which in my opinion gives great insight into Craig Venter's thinking. Both of these books are a pleasure to read for anyone curious about the way life works. Science at its best.
29 of 35 people found the following review helpful.
Craig, from the heart..
By R. Barton
The fact that Dr. Venter is writing another book is cause for me to drop everything, download and read it same day. And that excitement carried all the way through. This is a profound and incredible book on life and what makes it happen. He lays everything out transparently, all his ideas and reasonings and methods. He's just really smart and hardworking and those two things are at the root of his success, and success far beyond his time is what he has already accomplished. 'Some people see chaos, others see patterns' describes Dr. Venter's own mentality. I was astounded at how comprehensively he sees life, the cell and dna synthesis.
Someone floated a rumor (a chief rival?) in the past about Dr. Venter's ego and hubris and all that. When, where? I've never seen that from him and this book is further a credit to all those he works with. When he creates something he just says 'I did this' and I think he's allowed. Dr. Venter has been, like many in his field, one of the great assets to humankind. This book was conversational, like a fireside chat and I consumed it in a day. I couldn't get too much of his brilliance.
One thing I will note about this book, it closes the door on religion, vitalism and mysticism.
6 of 6 people found the following review helpful.
next life
By Renato Baserga
well narrated by the expert in the field. It is a fascinating story, and actually Venter underplays it as he does not delve into the multiple applications that can be derived from "new" cells. I am sure he is aware of what can be done with new cells, but somehow he does not spell it out, leaving it mostly to the reader's imagination. But Venter has been the first in other things, and it does not surprise me that he wanted to the first in replacing a "useless" nucleus with one made to order. Good luck to him; he deserves it.
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